An Unlikely Friendship

Listeria Meningitis: An Unlikely Pathogen in an Unlikely Host

Although a broad range of organisms must be considered in the diagnosis of infectious meningitis, viral and bacterial causes are most commonly observed. Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis are some of the more commonly isolated pathogens in bacterial meningitis. This illness typically presents with a well-documented set of signs and symptoms. The followi...

Aging: Cancer – an unlikely couple

Caffey disease: an unlikely collagenopathy.

Infantile cortical hyperostosis (also known as Caffey disease) is characterized by hyperirritability, acute inflammation of soft tissues, and profound alterations of the shape and structure of the underlying bones, particularly the long bones, mandible, clavicles, or ribs. In this issue of the JCI, Gensure et al. undertook fine mapping of the genetic locus for this disease in a large kindred of...

From bench to museum—an unlikely journey

Deciding to “leave the bench” and basic research after committing many, many years to graduate school is not an easy thing to do. There is real pressure from peers, principal investigators (PIs), even parents, to stick it out and follow a more established career path, either to academia or the biotech industry. In my case, I realized fairly early on in graduate school that the traditional optio...

Concept Maps and AI: an Unlikely Marriage?

Concept maps are a graphical representation of a person’s (or group of persons’) understanding of a domain. As such, it can be considered a knowledge representation scheme. However, the Artificial Intelligence (AI) community frowns on the use of the term “knowledge representation” to refer to concept maps, because they cannot be readily translated to a formal representation for inference or oth...